Flash column chromatography was developed in 1978 as an alternative method to long column chromatography. The method aims to isolate a component from a mixture and thereby purify it. It was built from ...

Table 1 Substrates of human matrix metalloproteinases. Figure 1: The domain structures of secreted-type matrix metalloproteinases (MMPs) and membrane-anchored MMPs. Figure 2: Purification steps of ...

Case in point: For more than a century, chromatography practitioners have been separating the components of chemical mixtures by using columns packed with various types of particulate matter. Recently ...

What is 2D liquid chromatography? Two-dimensional (2D) liquid chromatography is a powerful tool to separate complex compound mixtures. The principle behind 2D liquid chromatography is that compounds ...

Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...