True IgE-mediated local anesthetic hypersensitivity is <1% of reported reactions, so risk reduction should prioritize preservative-free amide selection, minimal effective dosing, and strict avoidance ...

1 Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia. An increasing number of HLA associations have been observed with drug-hypersensitivity ...

Please provide your email address to receive an email when new articles are posted on . 84.8% of patients who followed the protocol completed CT scans without any adverse reaction. 53.3% of patients ...

Hypersensitivity reactions induced by proton pump inhibitors (PPIs) represent a growing concern given the extensive use of these agents for managing acid-related disorders. Although PPIs are generally ...

—An analysis of registry data concluded that hypersensitivity reactions in patients with mastocytosis are caused by exposure to certain triggers, including low tryptase levels and stings from certain ...

Please provide your email address to receive an email when new articles are posted on . Percentages of patients who experienced breakthrough reactions decreased from 70% to 52% and then 43%.

Hypersensitivity reactions to vaccines occur in 1 in 50,000 to 1 in 100,000 doses. Most are local reactions and allow for the completion of the vaccination series. Systemic reactions are a minority ...

Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...