Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to synaptic strengthening.

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining ...

A study shows Munc13-1 regulates synaptic strengthening via calcium signaling, enabling efficient neurotransmission and ...

Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...

Video depiction of vesicle fusion and tethering. In the active zone in the central left of the video, docked vesicles (dark blue) fuse with the membrane, releasing their contents and being quickly ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...

Max Delbrück Center for Molecular Medicine in the Helmholtz Association Researchers led by Uljana Kravčenko and her colleagues in the lab of Professor Misha Kudryashev, Group Leader of the In Situ ...